A report on how the 1952 outbreak of foot-and-mouth disease in Saskatchewan was brought under control. The film describes how the disease affects cloven-hoofed animals, then shows the destruction and burial of all infected and exposed animals, and the imposition of strict quarantine measures to prevent any escape of the highly contagious virus beyond the buffer zone. The meticulous disinfection of farms, vehicles and all potental carriers is described. Finally, before the quarantine was lifted, we see how test animals were employed to make sure that all danger of contagion had passed.